BioPharma Capital

Your business development partner and strategic advisor

BioPharma Capital, LLC provides life sciences focused investment banking services, including M&A Advisory, strategic partnering and financing transaction management.

We are dedicated to maximizing value for our clients using credible scientific and evidence driven approaches. Our clients are typically pharmaceutical and biotech companies considering partnering, out-licensing, divestitures, fund raising or corporate sales.

Our team provides decades of experience in transaction support, healthcare strategy consulting, pricing and market access, forecasting, investment banking and translational research. We understand the science and technology behind the assets we represent and we have vast expertise managing transactions.

Insight into value through deep data

Our team has decades of experience in valuation work. Our philosophy is that validation of data through multiple sources yields higher fidelity and more credible valuations. Consequently, we endeavor to incorporate as many complementary data sources into our valuation work as possible.

We access numerous secondary sources to build a composite framework for valuation analysis, and we are able to integrate information from disparate sources into a single cohesive analytical structure. Additionally, we have the expertise to strategically integrate primary research into our asset valuations, having conducted more than 1,000 primary research interviews with clinicians, payers, and other experts from the US and EU.

Importantly, we understand that data and valuation analysis is unlikely to achieve the desired effect in negotiations without a clearly articulated value story to accompany the quantitative aspects of the work. Our valuation work goes beyond the numbers to provide a compelling case for the value and valuation that your asset or company possess.

We are dedicated to creating value for life science companies

We specialize exclusively in life sciences strategic advisory and transaction services. Our clients have included 15 of the top 20 pharma/biotech companies and dozens of small and mid-size biotech and spec pharma companies. We have experience working across all stages of the product lifecycle, from research collaborations and lead identification to in-line growth strategies and lifecycle planning.

Partner to provide strategic direction and drive towards optimal transactions

Partner to provide strategic direction and drive towards optimal transactions Partner to provide strategic direction and drive towards optimal transactions Commercial PotentialPositioningValuation Negotiations & Deal Structuring Transaction Execution Business Development Strategy What indicationsis the market mostinterested in? What activitieswill result in a stepup in valuation?What are the risks? What is the commercialattractiveness of the asset?How should it bepositioned? What is theright timing toenter a transaction? How much capitalis required to takethis forward?How does this dilutecurrent investors? What is thepotential increasein value ifadvanced to Ph II? What is the valueof the platform orpipeline versuslead asset? What is theinvestment horizonof current investors? What is theappropriate valuation?How is that bestarticulated? Whichcounterpartywill ensuresuccess? What is thedesired dealstructure? How dovarious termsheetscompare? Positioning 1 Positioning 2 Positioning 3 M&A Licensing Financing M&A Licensing Financing Phase I Completion Phase II Completion

Our Approach

BioPharma Capital (BPC) offers investment banking services focused on creating value for life science companies

Who We Are

  • Our team is passionate about maximizing value for our clients using credible scientific and evidence-driven strategies
  • We have decades of experience in transaction advisory, health care strategy consulting, pricing and market access, forecasting, investment banking, and translational research
Value
Creation

Who We Serve

  • Our clients are typically pharmaceutical and biotech companies considering partnering, licensing, co-development, co-promotion, or corporate sales
  • We work with assets in all therapy areas and in all stages of development, from pre-clinical discovery to marketed products
Leadership & Team
  • 2 Senior Advisors, 3 Project Managers, 4 Analysts
  • Access to highly qualified teams as-needed via professional networks
Activities Supported
  • Licensing, Partnering, Co-Promotion, and M&A
  • Due diligence, structuring, negotiations and valuation analyses
  • Serve as outsourced or extension of internal BD team
Fee Structures
  • Our flexible fee structures align incentives and accommodate client needs

Discussions with potential partners require strategic negotiations skills, persistence, and analytical rigor

BPC offers the focus, expertise and experience to successfully navigate partnering negotiations

Negotiations

  • Lead and participate in non-confidential and confidential discussions
  • Maintain active communication with your company team and coordinate scheduling with external parties including bidders and other vendors
  • Provide guidance on term sheet valuations and counteroffers

Financial Modeling & Deal Structuring

  • Build and maintain a model to generate term sheets and create rationale for offers/counteroffers or alternate structures that accommodate different viewpoints between partners
  • Adapt NPV model as new insights on inputs are gained and use new outputs to adapt deal materials accordingly

Data room

  • Monitor data room activities as per degree of visibility defined by host site
  • Update materials to adapt to possible partner concerns

We offer services tailored specifically to biopharma deal-making that are designed to surpass both IB and consulting offerings

Transaction Advisor Rigorous, Data-Driven Life-Science Market Insights Will go at-risk with clients to align interests Extensive Networks Deal brokering and execution
Investment Banks
Healthcare Consultants
BioPharma Capital

BioPharma Capital has capabilities and resources to provide strategic transaction advisory to life science companies

Strategic Advisory

An emphasis on optimizing value

BioPharma Capital, LLC has in-depth knowledge and global resources for emerging biopharma companies.

M&A

M&A Sell-Side Engagements

We can help you

  • Refine your pitch using our deep expertise in the pharmaceutical industry and understanding of what resonates with potential acquirers
  • Credibly articulate and validate your commercial opportunity by leveraging available third-party healthcare data and analytics
  • Target acquirers through our vast network in the life sciences industry

M&A Buy-Side Engagements

BioPharma Capital, LLC can leverage extensive experience with healthcare data to identify and evaluate acquisition targets to understand their full potential and aid in term sheet negotiations.

Our deep connections with global and regional executives across the biopharma industry will give you rapid, targeted access to the right stakeholders and visibility into their willingness to engage in a transaction. Access to sales force data allows us to accurately model the impact of an acquisition on the business and financials, including potential resulting synergies.

Partnering/Licensing Engagements

We can help you

  1. 01

    Refine your pitch using our deep expertise in the pharmaceutical industry and understanding of what resonates with potential partners

  2. 02

    Credibly articulate your commercial opportunity by accessing third-party healthcare data and analytics

  3. 03

    Target both global and regional partners through our vast network in the life sciences industry

  4. 04

    Structure transactions including upfront payments, milestones and royalties

  5. 05

    Negotiate and execute transactions

BPC ensures that the engagement process is well-orchestrated and runs at the proper cadence

Our process is designed to provide the most opportunities to solicit interest from the broadest possible set of potential partners and achieve the most favorable terms

PARTNERING ENGAGEMENT ACTIVITY SCHEMATIC PARTNERING ENGAGEMENT ACTIVITY SCHEMATIC Mgmt Team Board No Interest Interest No CDA Executed CDA No Interest Interest Interest No Interest Blinded 2-Pager GatherFeedback,ReviseMaterials Propose CDA Non-ConfidentialPresentation ConfidentialPresentation GatherFeedback,ReviseMaterials Non-bindingTerms Sheet OpenDataroom ContractNegotiations GatherFeedback,ReviseMaterials PartneringTransaction Illustrative

BPC quantifies term sheets to facilitate comparison of offers and provide guidance on counter-offers

Net increase in NPV from initial term sheet to current term sheet Net increase in NPV from initial term sheet to current term sheet $ Millions (except descriptors on x-axis) $400 $450 $500 $550 $600 $650 $700 $526.5 $23.8 $7.3 $68.4 $6.3 $15.0 $15.0 $619.7 Previousterm sheet Addterritory IncreaseFTE rate Royalty+1% (alltiers) ReduceUpfront Add Option@ end ofPhase 1 RemoveMilestone @start ofPhase 2 Revised offer Illustrative
  • Quantification of deal terms enables a uniform comparison of offers with differing milestones and payment options
  • Our analysis forms the basis for developing counter-offers to potential partners, and a supporting rationale to use in negotiations

Case Studies

Case studies available on request

Contact Us

Financing

With BioPharma Capital you have a valued partner

We seek to understand and target the right investors that align with our clients’ objectives and management style.

A Partner to Our Clients

We raise capital for our clients to accelerate growth by

  1. 01

    Accessing our vast network of healthcare investors

  2. 02

    Helping to successfully articulate their value and potential to investors

  3. 03

    Developing independent, third-party valuation analyses leveraging the multitude of data and expertise available to BioPharma Capital to credibly support pre-money valuations

  4. 04

    Leveraging our experience to structure the financing and negotiate terms

A Resource to Investors

BioPharma Capital provides sophisticated investors with unique pre-screened deal flow, offering an efficient way to identify opportunities that suit your objectives.

We conduct rigorous due diligence on potential opportunities, specifically screening for

  • Compelling science

  • Robust intellectual property

  • Experienced management team

  • Attractive commercial potential

  • Sound business strategy

  • Clear roadmap to value creation

Representative Transactions

Representative transactions available on request

Contact Us

Transactions

The BPC Team has supported over $12B in announced transaction value

$1B siRNA 2MW7141 Global License

Sell-side Advisor

$2.6B Disitamab Vedotin Global License

Sell-side Advisor

$400M Acquisition of

Buy-side Advisor

$1.26B Acquisition of

Co-Sell-side Advisor

$850M Co-Dev/Co-Promo

Buy-side Advisor

Undisclosed Collaboration and Option to Acquire

Sell-side Advisor

$310M Acquisition of

Sell-side Advisor

$230M Acquisition of

Buy-side Advisor

$650M Acquisition of

Buy-side Advisor

Undisclosed Option for Oncology Program

Sell-side Advisor

$290M KB001 Global License

Sell-side Advisor

Gabapentin SR US License

Sell-side Advisor

Not Exhaustive

2021 RemeGen–Seagen deal was highly covered by top media outlets in the industry

Seagen RemeGen

Seagen and RemeGen Announce Exclusive Worldwide License and Co-Development Agreement for Disitamab Vedotin

08/09/2021

– Seagen Licenses Disitamab Vedotin, a Novel HER2-targeted Antibody-Drug Conjugate (ADC) from RemeGen –

– Disitamab Vedotin has Shown Potential as a Differentiated ADC Across a Range of HER2 Expressing Tumors and is Being Developed as Monotherapy and in Combination with PD-1 Inhibitors, Further Expanding and Complementing Seagen’s Deep and Diverse Pipeline –

– Agreement Leverages Seagen and RemeGen’s Leadership and Expertise in Developing ADCs as well as Seagen’s Global Development and Commercialization Capabilities –

BOTHELL, Wash. & YANTAI, China--(BUSINESS WIRE)-- Seagen Inc. (Nasdaq: SGEN), a world leader and pioneer in antibody-drug conjugate (ADC) therapies, and RemeGen Co., Ltd. (9995.HK), a leading innovative biopharmaceutical company in China, today announced that the two companies have entered into an exclusive worldwide licensing agreement to develop and commercialize disitamab vedotin, a novel HER2-targeted ADC.

Disitamab vedotin combines the drug-linker technology originally developed by Seagen with RemeGen’s novel HER2 antibody exhibiting higher affinity and an increased internalization rate as compared to trastuzumab in preclinical models.1, 2 As monotherapy, disitamab vedotin has demonstrated antitumor activity in

https://investor.seagen.com/press-releases/news-details/2021/Seagen-and-RemeGen-Announce-Exclusive-Worldwide-License-and-Co-Development-Agreement-for-Disitamab-Vedotin/default.aspx
FiercePharma

In $2.6B cancer deal, Seagen bets China's first homemade ADC can challenge Roche, AZ-Daiichi

By Angus Liu · Aug 9, 2021 10:21am

https://www.fiercepharma.com/pharma/taking-aim-at-roche-and-astra-daiichi-seagen-bets-up-to-2-6b-china-s-first-home-made-adc
BioSpace

Seagen Strikes $2.6 Billion ADC Deal with China’s RemeGen

Seagen, formerly known as Seattle Genetics, forged an exclusive licensing agreement with China’s RemeGen Co., Ltd, to develop and commercialize disitamab vedotin, a novel HER2-targeted antibody drug conjugate (ADC). The deal is valued at about $2.6 billion.

Disitamab vedotin combines the drug-linker technology developed by Seagen with RemeGen’s novel HER2 antibody.

https://www.biospace.com/article/seagen-strikes-2-6-billion-adc-deal-with-china-s-remegen/

RemeGen-Seagen was ranked as the largest out-licensing deal from China in 2021

Top 10 China Out-Licensing deals in 2021

Licensee Licensor Regional Right Assets Disease Area Deal Value (US$m)
SeagenRemeGenGlobalDisitamab VedotinOncology2600
NovartisBeiGeneex-ChinatislelizumabOncology2200
LillyRegor Therapeuticsex-ChinaGLP-1RMetabolic Disease1500
FibroGenHiFiBioGlobalGalectin-9, and exclusive option for CXCR6 and CCR8Oncology1125
CoherusJunshi BiosciencesUS and CanadaToripalimabOncology1110
NovartisBeiGeneex-ChinaOciperlimab (BGB-A1217)anti-cancer therapy1000
BiogenInnoCareex-ChinaorelabrutinibAutoimmune937.5
ArriVentAllistex-ChinafurmonertinibOncology805
BeiGeneNanjing Leads Biolabsex- ChinaLBL-007 Anti-LAG-3 AntibodyOncology742
Flame BiosciencesNovaRock Biotherapeutics (Subsidiary of CSPC)ex- Greater ChinaNBL-015Oncology640

Source: “2021 China Biopharma Review”, MSQ Analytics, January 11th, 2022

BioPharma Capital Team Members

Our team is comprised of individuals with business development, licensing, investment banking, and pricing and market access expertise. We understand the science and technology behind the assets we represent and we have vast expertise managing transactions. This combination of talent and a network of connections provides our clients with exceptional service.

Dan Ross

Dan Ross

Managing Partner – BioPharma Capital, LLC

ph: +1 619 208-8439

dan@biopharmacapital.com

Current responsibility

  • Pitch, negotiate and close successful transactions on behalf of clients
  • Continue to expand professional network amongst strategic buyers and institutional investors

Profile overview

  • Experienced in several therapeutic areas
  • Expanded BD advisory relationship with RemeGen, serving as Chief Business Officer 2022-2024
  • Previously served as Chairman, President and CEO of IMS Health Capital
  • Started in health care at SalomonSmithBarney Investment Banking Division (New York / London)

Education

  • M.B.A. from Stanford University Graduate School of Business
  • Bachelor’s degree from San Diego State University

Areas of expertise

  • Deal brokering
  • Strategic advisory
  • Transaction structuring
  • Negotiations
  • Valuation

Relevant experience

  • M&A, Financing, Partnering Transactions
  • Business development strategy consulting
Annaly Godwin

Annaly Godwin

Director – BioPharma Capital, LLC

annaly@biopharmacapital.com

Current responsibility

  • 9+ years driving business development, partnerships, and transaction support in fast-paced, client-facing environment
  • Advises healthcare professionals on licensing and M&A opportunities, combining strong relationship-building with a global network across MNCs, investors, and industry leaders

Education

  • Masters National University
  • Bachelor of Arts National University

Relevant Experience

  • Supported execution of major BPC client transactions, including the $2.6B SeaGen–RemeGen deal advancing disitamab vedotin globally, the $1B Mabwell–Aditum newco transaction establishing Kalexo, and the $500M Genentech/Roche-Convelo transaction
  • Member of RemeGen’s business development team, contributing to multiple term sheets from top MNCs; recipient of the Excellent Department Award 2022
  • Built strategic partnerships, improved processes, and identified growth opportunities through industry research

Areas of expertise

  • Partnerships, networking, desk research, competitive analyses and outreach
  • Healthcare licensing, M&A, and valuation
  • Completed formal investment banking training
Chloe Autran

Chloe Autran

Director – BioPharma Capital, LLC

chloe@biopharmacapital.com

Current responsibility

  • Translate complex science into clear strategic positioning and partnering narratives for biotechnology transactions
  • Develop valuation analyses, competitive landscapes, and asset positioning strategies for early-stage therapeutic and platform companies

Education

  • PhD – Technical University of Munich / UC San Diego
  • MSc – Reproductive Endocrinology, University of Idaho
  • BSc – Colorado State University

Relevant Experience

  • 6+ years integrating translational science and commercial strategy to position biotechnology innovations for investment and partnering success
  • Leadership in fundraising, corporate strategy, and strategic partnerships for early-stage biotechnology companies
  • Experience advancing innovation programs across R&D, clinical development, and business development functions
  • PhD-trained researcher specializing in microbiology, immunology, and glycobiology

Areas of Expertise

  • Biotech Partnering & Licensing Strategy
  • Translational Biology & Microbiome Science
  • Investor Communications
  • Diligence preparation and VDR management

Any testimonial or endorsement may not be representative of the experience of other customers and is no guarantee of future performance or success.

Contact Info

BioPharma Capital, LLC

Office
La Jolla, CA
USA
Phone
+1 619 208-8439
Email
info@biopharmacapital.com

Dan Ross, MBA

Role
Managing Partner
Phone
+1 619 208-8439
Email
dan@biopharmacapital.com

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